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Functions being a loading platform to recruit DDR proteins that let completion of DNA replication soon after DNA hurt and boost postreplication maintenance: Monoubiquitinated PCNA results in recruitment of translesion (TLS) polymerases, although 'Lys-63'-joined polyubiquitination of PCNA is involved in mistake-absolutely free pathway and employs re

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HY and JL created the evaluate’s concept and framework and contributed to penning this evaluate. XL, LM, and MH participated in a lot of the writing. HZ and RZ revised and finalized the critique. All authors browse and approved the final manuscript.The investigators will likely assess if this new drug decreases nicotine withdrawal, craving, and c

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